Abstract
Ten Alzheimer's disease patients underwent a trial of oral tetrahydroaminoacridine (THA) and lecithin. After 3 inpatient weeks there was no clear therapeutic effect. Three of six patients able to continue in long-term treatment showed measurable cognitive improvement, but only one displayed clinically obvious improvement.
Publication types
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Clinical Trial
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Controlled Clinical Trial
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Aged
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Alzheimer Disease / drug therapy*
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Aminoacridines / therapeutic use*
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Clinical Trials as Topic
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Double-Blind Method
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Drug Therapy, Combination
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Humans
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Male
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Phosphatidylcholines / therapeutic use*
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Tacrine / therapeutic use*
Substances
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Aminoacridines
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Phosphatidylcholines
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Tacrine