Abstract
The inhibitory effect of saponins from Tribulus terrestris (STT) on Bcap37 breast cancer cell line were determined by cell growth curve, MTT assay, protein content assay and morphological observation. The results showed that STT had potent inhibitory effect on Bcap-37 cell line in a concentration-dependent manner. Bcap-37 cell exhibited morphological alteration, namely, cells got round and shrunk, nuclei contracted after treating with STT.
MeSH terms
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Antineoplastic Agents, Phytogenic / pharmacology*
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Breast Neoplasms / metabolism
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Breast Neoplasms / pathology*
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Carcinoma, Medullary / metabolism
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Carcinoma, Medullary / pathology
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Cell Division / drug effects
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Drugs, Chinese Herbal / pharmacology
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Female
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Humans
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Neoplasm Proteins / metabolism
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Plants, Medicinal / chemistry*
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Prohibitins
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Saponins / isolation & purification
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Saponins / pharmacology*
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Tribulus / chemistry*
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Tumor Cells, Cultured
Substances
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Antineoplastic Agents, Phytogenic
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Drugs, Chinese Herbal
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Neoplasm Proteins
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PHB2 protein, human
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Prohibitins
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Saponins