Dr. Jean-Claude Lavoie
University of
Montreal, Canada
Email: Jean-claude.lavoie@umontreal.ca
Qualifications
1998 Ph.D.,
Biomedical Sciences, University of Montreal, Canada
1992 M.Sc.,
Biomedical Sciences, University of Montreal, Canada
1989 Diploma,
Graduate Study Diploma Specialized in Toxicology, University of Montreal,
Canada
1983 Diploma, Undergraduate Certificate in Environmental Sciences,
Université du Québec à Montréal, Canada
1976 B.Sc.,
Biochemical, University of Montreal, Canada
Publications(Selected)
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Harrison A, Khashu
M, Friel J, Lavoie JC, Chessex P. Variations in metabolic response to TPN
are influenced more by gender than light exposure. J Pediatr Gastroenterol Nutr
45:577-581, 2007
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Chessex P, Harrison
A, Khashu M, Lavoie JC. In preterm neonates, is the risk of
developing bronchopulmonary dysplasia influenced by the failure to protect
total parenteral nutrition from exposure to ambient light? J Pediatr
151:213-214, 2007
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Levy E, Trudel K,
Bendayan M, Seidman EG, Delvin E, Elchebly M, Lavoie JC, Precourt LP, Amre
D, Sinnett D. Biological role, Protein Expression, Subcellular Localization and
Oxidative Stress Response of Paraoxonase2 in the Intestine of Humans and Rats.
Am J Physiol Gastrointest Liver Physiol. 293:G1252-61, 2007
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Yang C, Mwaikambo
RB, Zhu T, Gagnon C, Seshadri S, Lachapelle P, Lavoie JC, Chemtob S, Hardy
P. Lymphocytic microparticles inhibit angiogenesis by stimulating
oxidative stress and negatively regulating VEGFinduced pathways, AJP-
Regulatory, Integrative and Comparative Physiology 294:R467-76, 2008
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Lavoie JC, Rouleau
T, Tsopmo A, Friel J, Chessex P. Influence of lung oxidant and antioxidant
status on alveolarization: role of light-exposed total parenteral nutrition.
Free Radic Biol Med 45:572-577, discussion 570-1, 2008
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Yzydorczyk C, Comte
B, Cambonie G, Lavoie JC, Germain N, Shun YT, Wolff J, Deschepper C, Touyz RM,
Lelievre-Pegorier M, Nuyt AM. Neonatal oxygen exposure in rats leads to
cardiovascular and renal alterations in adulthood. Hypertension 52:889-95, 2008
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Khashu M, Harrison
A, Lalari V, Lavoie JC, Chessex P. Impact of shielding parenteral nutrition
from light on routine monitoring of plasma glucose and triglyceride in preterm
neonates. Arch Dis Child Fetal Neonatal 94:F111-5, 2009
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Turcot V, Nuyt AM,
Rouleau T, Tsopmo A, Germain N, Potvin L, Lavoie JC. Long-term impact of a
deficient neonatal diet to sustain the antioxidant defence on the lipid and
glucose metabolism. Free Radic Biol Med 47 :275-282, 2009
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Chessex P, Khashu M,
Harrison A, Hosking M, Sargent M, Lavoie JC. Early life events, sex and
arterial blood pressure in critically ill infants. Pediatric Crit Care Med
11:75-81, 2010
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Zaniolo K,
St-Laurent JF, Gagnon SN, Lavoie JC, Desnoyers S. Photoactivated multivitamin
preparation induces poly(ADP-ribosyl)ation, a DNA damage response in mammalian
cells. Free Radic Biol Med, 48:1002-12, 2010
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Maghdessian R, Côté
F, Rouleau T, Ouadda ABD, Levy E, Lavoie JC. Ascorbylperoxide
contaminating parenteral nutrition perturbs the lipid metabolism in newborn
guinea pig. J Pharmacol Exp Ther 334:278-284, 2010
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Kleiber N, Rouleau
T, Nuyt AM, Chessex P, Perreault M, Lavoie JC. Neonatal exposure to
oxidants induces later in life a metabolic response associated to a phenotype
of energy deficiency in an animal model of TPN. Pediatr Res 68:188-92, 2010
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Lavoie P, Lavoie JC,
Watson C, Rouleau T, Chang BA, Chessex P. Inflammatory response in preterm
infants is induced early in life by oxygen and modulated by TPN. Pediatr
Res 68:248-51, 2010
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Chessex P, Watson C,
Kaczala G, Rouleau T, Lavoie ME, Friel J, Lavoie JC. Determinants of
oxidant stress in extremely low birth weight premature infants. Free Radic Biol
Med 49 :1380-6, 2010
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Précourt LP, Amre D,
Denis MC, Lavoie JC, Delvin E, Seidman E, Levy E. The three-gene paraoxonase
family: Physiologic roles, actions and regulation. Atherosclerosis.
214(1):20-36, 2010
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Tsopmo A, Romanowski
A, Banda L, Lavoie JC, Jenssen H, Friel J. Novel anti-oxidative peptides from
enzymatic digestion of human milk. Food Chem 126 :1138-1143, 2011
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Marcil V, Lavoie JC,
Emonnot L, Seidman E, Levy E. Analysis of the effects of iron and vitamin C
cosupplementation on oxidative damage, antioxidant response and inflammation in
THP-1 macrophages. Clin Biochem 44 :873-883, 2011
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Lavoie ME, Ziai S,
Rabasa-Lhoret R, Lavoie JC. Blood glutathione peroxidase activity in
relation with the risk of cardiovascular diseases in obese woman. J Diabetes
Metab 2:136, doi:10.4172/2155-6156.1000136, 2011
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Lavoie JC, Mohamed
I. Bronchopulmonary dysplasia: The role of oxidative stress. In: Lung Diseases
– Selected State of the Art Reviews. Ed: Elvis Malcolm Irusen, Publisher :
InTech, 22 :485-504, ISBN 978- 953-51-0180-2, 2012
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Miloudi K, Comte B,
Rouleau T, Montoudis A, Levy E, Lavoie JC. The mode of administration of
total parenteral nutrition and nature of lipid content influence the generation
of peroxides and aldehydes. Clin Nutr, doi:10.1016/j.clnu.2012 Jan 7, 2012