Biography

Dr. Jose C. Jimenez-Lopez

Spanish National Research Council (CSIC)
Estacion Experimental del Zaidin
Dpt. Biochemistry, Cell & Molecular Biology of Plants
Granada, Spain


Email: josecarlos.jimenez@eez.csic.es


Qualifications

2021–Onwards Tenured Scientist at CSIC, Granada, Spain

2016–2021 Ramon y Cajal Research Fellow at The Spanish National Research Council (CSIC), Granada, Spain

2012–2015 Marie Curie Research Fellow (EU FP7-IOF) at The University of Western Australia (UWA), Perth, Australia

2008–2011 Full-Time Postdoctoral Research Associate at Purdue University, IN USA

2008 Ph.D., Spanish National Research Council (CSIC), Spain

2004 M.S., Agricultural Sciences - University of Granada, Spain

2001 B.S., Biological Sciences – University of Granada, Spain

1998 B.S., Biochemistry & Molecular Biology – University of Granada, Spain


Publications (Selected)

  1. Clemente A, Jimenez-Lopez JC. (2020). Legumes as food ingredient: Characterization, processing, and applications. FOODS 9(11), 1525; doi: 10.3390/foods9111525
  2. Jimenez-Lopez JC, Singh KB, Clemente A, Nelson MN, Ochatt S, Smith PMC. (2020). Editorial: Legumes for Global Food Security. FRONTIER IN PLANT SCIENCE 11: 926; doi: 10.3389/fpls.2020.00926
  3. Jimenez-Lopez JC. (2020). Narrow-leafed lupin (Lupinus angustifolius L.) β-conglutin: a multifunctional family of proteins with roles in plant defence, human health benefits and potential uses as functional food. LEGUME SCIENCE e33; doi: 10.1002/leg3.33
  4. Lima-Cabello E, Alché JD, Morales-Santana S, Clemente A, Jimenez-Lopez JC. (2019). Narrow-leafed lupin (Lupinus angustifolius L.) seeds gamma-conglutin is an anti-inflammatory protein promoting insulin resistance improvement and oxidative stress amelioration in PANC-1 pancreatic cell-line. ANTIOXIDANTS 9(1), 12; doi: 10.3390/antiox9010012
  5. Maestri D, Barrionuevo D, Bodoira R, Zafra A, Jimenez-Lopez JC, Alché JD. (2019). Nutritional profile and nutraceutical components of olive (Olea europaea L.) seeds. JOURNAL OF FOOD SCIENCE AND TECHNOLOGY 56(9): 4359-4370; doi: 10.1007/s13197-019-03904-5
  6. Lima-Cabello E, Alché JD, Jimenez-Lopez JC. (2019). Narrow-leafed lupin main aller-gen beta-conglutin (Lup an 1) detection and quantification assessment in natural and processed foods. FOODS 8(10), 513; doi: 10.3390/foods8100513
  7. Zafra A, M'rani-Alaoui M, Lima-Cabello E, Jimenez-Lopez J.C., Alché J.D. (2018). Histo-logical features of the olive seed and presence of 7S-type seed storage proteins as hall-marks of the olive fruit development. FRONTIERS IN PLANT SCIENCE 9: 1481; doi: 10.3389/fpls.2018.01481
  8. Lima-Cabello, Morales-Santana S, Leon J, Alche V, Clemente A, Alche JD, Jimenez-Lopez J.C. (2018). Narrow-leafed lupin (Lupinus angustifolius L.) seed β-conglutins re-verse back the induced insulin resistance in pancreatic cells. FOOD & FUNCTION 9: 5176-5188; doi: 10.1039/C8FO01164H
  9. Lima-Cabello E, Morales-Santana S, Foley RC, Melser S, Alche V, Siddique KHM, Singh KB, Alche JD, Jimenez-Lopez JC. (2018). Ex vivo and in vitro assessment of anti-inflammatory activity of seed β-conglutin proteins from Lupinus angustifolius. JOURNAL OF FUNCTIONAL FOODS 40: 510-519; doi: 10.1016/j.jff.2017.11.040
  10. Jimenez-Lopez J.C., Foley R.C., Brear E, Clarke V., Lima-Cabello E., Florido J.F., Singh K.B., Alché J.D., Smith P.M.C. (2018). Characterization of IgE-binding to the recombinant major seed allergen of Narrow-leafed lupin (Lupinus angustifolius L.) and to natural beta-conglutin counterparts of lupin seed species. FOOD CHEMISTRY 244: 60-70; doi: 10.1016/j.foodchem.2017.10.015
  11. Lima-Cabello E, Alche V, Foley RC, Andrikopoulos S, Morahan G, Singh KB, Alche JD, Jimenez-Lopez JC. (2017). Narrow-leafed lupin (Lupinus angustifolius L.) b-conglutin proteins modulate the insulin signalling pathway. MOLECULAR NUTRITION AND FOOD RESEARCH 61(5); doi: 10.1002/mnfr.201600819
  12. Jimenez-Lopez J.C., Foley RC, Brear E, Clarke VC, Lima-Cabello E, Florido JF, Singh KB, Smith PMC, Alche JD. (2017). Characterization of the differential IgE-binding fea-tures of lupinus angustifolius recombinant major allergen (Lup An 1) for potential uses in "sweet lupin" allergy diagnosis and therapy. ALLERGY 72(103); doi: 10.1111/all.13247
  13. Lima-Cabello E., Robles-Bolivar P., Alché J.D., Jimenez-Lopez J.C.* (2016). Narrow-leafed lupin β-conglutin proteins epitopes identification and molecular features analy-sis involved in cross-allergenicity to peanut and other legumes. GENOMICS AND COMPUTATIONAL BIOLOGY 2(1): e29; doi: 10.18547/gcb.2016.vol2.iss1.e29
  14. Jimenez-Lopez J.C., Robles-Bolivar P, Lopez-Valverde FJ, Lima-Cabello E, Kotchoni SO, Alche JD. (2016). Ole e 13 is the unique food allergen in olive: Structure-functional, substrates docking, and molecular allergenicity comparative analysis. JOURNAL OF MOLECULAR GRAPHICS AND MODELLING 66: 26-40; doi: 10.1016/j.jmgm.2016.03.003
  15. Jimene-Lopez J.C., Zafra A, Palanco L, Florido F, Alché JD. (2016). Identification and assessment of the potential allergenicity of 7S‐like SSPs in the olive (Olea europaea L.) seeds. BIOMED RESEARCH INTERNATIONAL Vol. 2016, Article ID 4946872; doi: 10.1155/2016/4946872
  16. Jimenez-Lopez J.C., Zienkiewicz A., Zienkiewicz K., Alché J.D., Rodriguez-Garcia M.I. (2016). Biogenesis of protein bodies during legumin accumulation in Olea europaea L. seed development and differentiation. PROTOPLASMA 253(2): 517-530; doi: 10.1007/s00709-015-0830-5
  17. Foley R.C., Jimenez-Lopez J.C., Kamphuis L.G., Hane J.K., Singh K.B. (2015). Analysis of conglutin seed storage proteins across Lupin species using transcriptomic, protein, and comparative genomic approaches. BMC PLANT BIOLOGY 15: 106; doi: 10.1186/s12870-015-0485-6
  18. Jimenez-Lopez J.C. (2015). Lupin (Lupinus angustifolius L.) b-conglutin proteins: Struc-ture functional features, catalytic mechanism modeling and cross-allergenicity identifi-cation using protein threading and molecular docking methods. PROTEIN SCIENCE 24; doi: 10.1002/pro.2823
  19. Jimenez-Lopez JC, Lima-Cabello E., Melser S., Foley R.C., Singh K.B., Alché J.D. (2015). Lupin allergy: uncovering structural features and epitopes of β-conglutin proteins in Lupinus angustifolius L. with a focus on cross-allergenic reactivity to peanut and other legumes. BIOINFORMATICS AND BIOMEDICAL ENGINEERING 9043: 96-107; doi: 10.1007/978-3-319-16483-0_10
  20. Jimenez-Lopez J.C., Kotchoni S.O., Hernandez-Soriano M.C., Gachomo E.W. & Alche J.D. (2013). Structural functionality, catalytic mechanism modeling and molecular allergenicity of phenylcoumaran benzylic ether reductase, an olive pollen (Ole e 12) allergen. JOURNAL OF COMPUTER-AIDED MOLECULAR DESING 27(10): 873-895; doi: 10.1007/s10822-013-9686-y
  21. Jimenez-Lopez J.C., Rodríguez-García M.I., Alche J.D. (2013). Analysis of the effects of polymorphism on pollen profilin structural functionality and the generation of con-formational, T- and B-cell epitopes. PLOS ONE 8(10): e76066; doi: 10.1371/journal.pone.0076066
  22. Jimenez-Lopez J.C., Kotchoni S.O., Rodríguez-García M.I. & Alché J.D. (2012). Structure and functional features of olive pollen pectin methylesterase using homology modeling and molecular docking methods. JOURNAL OF MOLECULAR MODELING 18(12): 4965-4984; doi: 10.1007/s00894-012-1492-2


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