We examine whether the consumption of low-glycemic index (GI) carbohydrates may facilitate a reduction in energy intake in obese people attempting to lose weight. Although data from long-term studies are lacking, short-term investigations indicate that consumption of low-GI carbohydrates may delay the return of hunger and reduce subsequent energy intake relative to consumption of higher-GI carbohydrates. While long-term research on GI and weight regulation is needed, current evidence suggests a potential role for low-GI carbohydrates in weight-reducing regimens.